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That's because Angular only checks if an array reference has changed. If you add new option or update parameter of existing option, the change detection won't be triggered. Here is an example:

HTML:

<div class="row">
  <div class="col-md-6">
    <mdb-select [options]="optionsSelect" placeholder="Choose your option"></mdb-select>
  </div>
</div>

TS:

import { Component, OnInit } from '@angular/core';

@Component({
  selector: 'app-root',
  templateUrl: './app.component.html',
  styleUrls: ['./app.component.scss'],
})
export class AppComponent implements OnInit {
  optionsSelect = [
    { value: '1', label: 'Option 1', disabled: false },
    { value: '2', label: 'Option 2', disabled: false },
    { value: '3', label: 'Option 3', disabled: false },
  ];

  ngOnInit() {
    setTimeout(() => {
      this.updateDisabledState(); // nothing happens here
      this.optionsSelect = [...this.optionsSelect] // array reference change, Angular will trigger change detection for options input
    }, 3000);
  }

  updateDisabledState() {
    this.optionsSelect.forEach(option => {
      option.disabled = true;
    })
  }
}